 |
|
|
|
|
|
|
If this is your first time using TRELSTAR, after your first injection you might feel a temporary increase in your cancer symptoms, such as pain in your bones. This is because the amount of testosterone in your bloodstream actually goes up for a short period after the injection. After a few days, it goes down as your body adjusts to the medicine.
If your symptoms worsen please speak to your doctor.
Side Effects
The most common side effects that patients taking TRELSTAR have may be due to the effect of lowering testosterone levels. The most common effect of lowering testosterone is hot flushes. Sexual side effects can also occur. Your doctor may be able to help with this problem.
|
|
|
|
|
Indications and Usage
TRELSTAR® Depot and TRELSTAR®
LA are indicated in the palliative treatment of advanced prostate cancer. TRELSTAR
Depot or TRELSTAR LA offer an alternative treatment for prostate cancer when orchiectomy
or estrogen administration are either not indicated or unacceptable to the patient. |
|
|
|
Safety Information
|
|
The most commonly reported adverse events associated with the use of TRELSTAR®
Depot/TRELSTAR® LA included hot flushes (58.6%/73.0%), skeletal pain
(12.1%/13.2%), impotence (7.1%/2.3%), headache (5.0%/6.9%), leg pain (2.1%/5.2%),
and edema in legs (0.0%/6.3%) . TRELSTAR is contraindicated in women who are or
may become pregnant as well as patients who are hypersensitive to triptorelin, other
LHRH agonists, or LHRH . Infrequent postmarketing reports of anaphylactic shock
and angioedema have been received since 1986 (global experience) . As with all LHRH
agonists, triptorelin causes an initial transient increase in testosterone levels.
Patients may experience the onset or exacerbation of symptoms during this period,
including bone pain, neuropathy, hematuria, spinal cord compression, or urethral
or bladder outlet obstruction. Patients with metastatic vertebral lesions and/or
urinary tract obstruction should be closely observed. |
|
|
|
|
|
|
|
|
|
