TRELSTAR - Choosing the TRELSTAR Formulation That Is Right For You

Choosing the TRELSTAR Formulation That Is Right For You
TRELSTAR comes in 2 different formulations. Your doctor will help you choose the one that is right for you. TRELSTAR Depot (3.75 mg) is given as an injection once every 4 weeks. The medication is released slowly into your bloodstream and is designed to keep your testosterone levels low for the whole month.

The other formulation is TRELSTAR LA (11.25 mg). The LA stands for “long-acting.” TRELSTAR LA is given as a shot once every 12 weeks. It is also released slowly and is designed to keep testosterone levels low until your next injection.

Treatment Regimen

Indications and Usage
TRELSTAR^® Depot and TRELSTAR^® LA are indicated in the palliative treatment of advanced prostate cancer. TRELSTAR Depot or TRELSTAR LA offer an alternative treatment for prostate cancer when orchiectomy or estrogen administration are either not indicated or unacceptable to the patient.

Safety Information

The most commonly reported adverse events associated with the use of TRELSTAR^® Depot/TRELSTAR^® LA included hot flushes (58.6%/73.0%), skeletal pain (12.1%/13.2%), impotence (7.1%/2.3%), headache (5.0%/6.9%), leg pain (2.1%/5.2%), and edema in legs (0.0%/6.3%) . TRELSTAR is contraindicated in women who are or may become pregnant as well as patients who are hypersensitive to triptorelin, other LHRH agonists, or LHRH . Infrequent postmarketing reports of anaphylactic shock and angioedema have been received since 1986 (global experience) . As with all LHRH agonists, triptorelin causes an initial transient increase in testosterone levels. Patients may experience the onset or exacerbation of symptoms during this period, including bone pain, neuropathy, hematuria, spinal cord compression, or urethral or bladder outlet obstruction. Patients with metastatic vertebral lesions and/or urinary tract obstruction should be closely observed.